Homing gene drive for suppression of spotted wing Drosophila

In a recent publication in PNAS, we report an efficient genetic system for control of Drosophila suzukii populations. The study was led by Amarish Yadav and describes a split Cas9-based gene drive that targeted the female-specific exon of the doublesex gene, which is essential for female development. The approach we took could be applied to other agricultural pests such as the New World screwworm.

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