Epigenetics

Schwartz, S., Truglio, M., Scott, M.J., and Fitzsimons, H.L. (2016) Long-term Memory in Drosophila Is Influenced by the Histone Deacetylase HDAC4 Interacting with the SUMO-Conjugating Enzyme Ubc9. Genetics. 203: 1249-1264. doi: 10.1534/genetics.115.183194 web

Linger, R.J., Belikoff, E.J. and Scott, M.J. (2015) Dosage Compensation of X-Linked Muller Element F Genes but Not X-Linked Transgenes in the Australian Sheep Blowfly. PLoS ONE 10(10): e0141544. web

Fitzsimons H.L., Schwartz S., Given F.M., Scott M.J. (2013) The Histone Deacetylase HDAC4 Regulates Long-Term Memory inĀ Drosophila. PLoS ONE 8(12): e83903. doi:10.1371/journal.pone.0083903 web

Fitzsimons, H.L. and Scott, M.J. (2011) Genetic modulation of Rpd3 expression impairs long-term courtship memory in Drosophila. PLoS ONE, 6(12): e29171. doi: 10.1371/journal.pone.0029171 web

Laverty, C., Li, F., Belikoff, E.J. and Scott, M.J. (2011) Abnormal dosage compensation of reporter genes driven by the Drosophila glass multiple reporter (GMR) enhancer-promoter. PLoS ONE, 6(5): e20455. doi:10.1371/journal.pone.0020455 web

Moore, S.A., Ferhatoglu, Y., Jia, Y., Al-Jiab, R.A. and Scott, M.J. (2010) Structural and biochemical studies on the chromo-barrel domain of male specific lethal 3 (MSL3) reveal a binding preference for mono or dimethyl lysine 20 on histone H4. J. Biol. Chem. 285: 40879-90. doi:10.1074/jbc.M110.134312 web

Schiemann, A.H., Li, F., Weake, V.M., Belikoff, E.J., Klemmer, K.C., Moore, S.A. and Scott, M.J. (2010) Sex-biased transcription enhancement by a 5′ tethered Gal4-MOF histone acetyltransferase fusion protein in Drosophila. BMC Molecular Biology, 11:80. doi:10.1186/1471-2199-11-80 web

Schiemann, A.H., Weake, V.M., Li, F., Laverty, C., Belikoff, E.J., and Scott, M.J. (2010) The importance of location and orientation of male specific lethal complex binding sites of differing affinities on reporter gene dosage compensation in Drosophila. Biochemical and Biophysical Research Communications, 402: 699-704. doi:10.1016/j.bbrc.2010.10.088. web

Li, F., Schiemann, A.H. and Scott, M.J. (2008) Incorporation of the non-coding roX RNAs alters the chromatin binding specificity of the Drosophila MSL1/MSL2 complex. Mol. Cell. Biol. 28: 1252-1264. doi:10.1128/MCB.00309-08 web

Scott, M.J. and Li, F. (2008) How do ncRNAs guide chromatin-modifying complexes to specific locations within the nucleus? RNA Biology 5: 13-16. web

Weake, V.M. and Scott, M.J. (2007) The non-dosage compensated Lsp1alpha gene of Drosophila melanogaster escapes acetylation by MOF in larval fat body nuclei, but is flanked by two dosage compensated genes. BMC Mol Biol, 8: 35. doi:10.1186/1471-2199-8-35 web

Li, F., Parry, D.A.D. and Scott, M.J. (2005) The amino-terminal region of Drosophila MSL1 contains basic, glycine-rich, and leucine zipper-like motifs that promote X chromosome binding, self-association, and MSL2 binding, respectively. Mol. Cell. Biol. 25: 8913-8924. doi: 10.1128/MCB.25.20.8913-8924.2005 web

Henry, R.A., Tews, B., Li, X. and Scott , M.J. (2001) Recruitment of the MSL dosage compensation complex to an autosomally integrated roX chromatin entry site correlates with an increased expression of an adjacent reporter gene in male Drosophila. J. Biol. Chem., 276: 31953-31958. doi:10.1074/jbc.M103008200 web

Scott, M.J. (2001) Making 1X=2X: Studies on dosage compensation in Drosophila. NZ BioScience 9 (4): 23-24.

Scott, M.J., Pan, L.L., Cleland, S.B., Knox, A.L. and Heinrich J.C. (2000) MSL1 plays a central role in assembly of the MSL complex, essential for dosage compensation in Drosophila. EMBO J., 19: 144-155. doi:10.1093/emboj/19.1.144 web

Fitzsimons, H., Henry, R. and Scott, M.J. (1999) Development of an insulated reporter system to search for cis-acting sequences required for dosage compensation in Drosophila. Genetica, 105: 215-226.

Zhou, S., Yang, Y., Scott, M.J., Pannuti, A., Fehr, K.C., Eisen, A., Koonin, E.V., Fouts, D.L., Wrightsman, R., Manning, J.E. and Lucchesi, J.C. (1995) Male-specific lethal 2, a dosage compensation gene of Drosophila, undergoes sex-specific regulation and encodes a protein with a RING finger and a metallothionein-like cysteine cluster. EMBO J. 14: 2884-2895.

Scott, M.J. and Lucchesi, J.C. (1991) Structure and expression of the Drosophila melanogaster gene encoding 6-phosphogluconate dehydrogenase. Gene 109: 177-183.

Scott, M.J., Tsai, M.-J. and O’Malley, B.W. (1987) Deoxyribonuclease I sensitivity of the ovomucoid-ovoinhibitor gene complex in oviduct nuclei and relative location of CR1 repetitive sequences. Biochemistry 26: 6831-6840.